kinase inhibitor-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16987	TAO Kinase inhibitor 1		Others , MAPK
	TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectiv...		Others , MAPK
T67755	Protein kinase G inhibitor-1		PKA
	Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.		PKA
T6335	Tie2 kinase inhibitor 1	Tie2 kinase inhibitor	Tie-2
	Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38.		Tie-2
T11184	EML4-ALK kinase inhibitor 1	EML4 ALK kinase inhibitor 1,EML4-ALK kinase inhibitor 1	ALK
	EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.		ALK
T4191	Multi-kinase inhibitor 1	Multi-kinase inhibitor I	Others , Bcr-Abl , PDGFR , c-Kit
	Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.		Others , Bcr-Abl , PDGFR , c-Kit
T6409	ALK kinase inhibitor-1	SAR348830	Others
	SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.		Others
T9229	Pim-1/2 kinase inhibitor 1		Pim
	Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim ...		Pim
T12725	RIP1 kinase inhibitor 1		Others
	RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04.		Others
T12396	PDGFRα kinase inhibitor 1		PDGFR
	PDGFRα kinase inhibitor 1 is a highly selective inhibitor of type II PDGFRα kinase (PDGFRα and PDGFRβ with IC50s of 132 nM and 6115 nM , respectively).		PDGFR
T83627	Pim-1 kinase inhibitor 8		Pim , PKC
	Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound ...		Pim , PKC
T12727	RIP2 kinase inhibitor 1		Others
	RIP2 kinase inhibitor 1 is a potent and selective receptor interacting inhibitor of protein 2 (RIP2) kinase(RIP2 FP with an IC50 of 0.03 μM ),and is used for autoinflammatory disorders.		Others
T17145	Tpl2 Kinase Inhibitor 1		Others
	Tpl2 Kinase Inhibitor 1 is an effective and selective Tpl2 inhibitor.		Others
T77526	Pim-1 kinase inhibitor 4		Apoptosis , Pim
	Pim-1 kinase inhibitor 4 is a potent Pim-1 kinase inhibitor with an IC50 value of 17.01 nM.Pim-1 kinase inhibitor 4 also possesses antioxidant activity and potential anticancer activity, and inhibits DPPH.Pim-1 kinase in...		Apoptosis , Pim
T11761	Tarlox-TKI	Kinase inhibitor-1	COX
	Kinase inhibitor-1 is a kinase inhibitor.		COX
T60688	MKI-1	MASTL Kinase Inhibitor-1	Others
	MKI-1 (MASTL Kinase Inhibitor-1) is an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like, IC50= 9.9 μM). MKI-1 exerts radiosensitizer and antitumor activities through PP2A activation in breast cance...		Others
T3593	Src Inhibitor 1	Src Kinase Inhibitor 1,Src-l1	Src
	Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.		Src
T8864	Thymidylate Kinase Inhibitor, YMU1		Others
	YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.		Others
T14692	BMX-IN-1	BMX kinase inhibitor	BTK
	BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine kinase (BTK, IC50 = 10.4 nM), but BMX-IN-1 is more than 47-656 ...		BTK
T9631	IRAK-4 protein kinase inhibitor 2		IRAK
	IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).		IRAK
T3101	NQDI-1	NQDI1,NQDI 1	Apoptosis , ASK , MAPK
	NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).		Apoptosis , ASK , MAPK